Jie Luo, PhD
Assistant Professor
Department of Industrial and Molecular Pharmaceutics
Jie Luo is a tenure-track Assistant Professor in the College of Pharmacy at Purdue University. His research focuses on developing advanced whole-body imaging techniques to establish the connection between physiology and pharmacology, thereby identifying new therapeutic targets.
Specialization: Tissue clearing; drug delivery, 3D omics mapping, and deep learning algorithm development.
Research Interests
We employ advanced whole-body imaging techniques to identify significant tissue areas. Using single-cell omics techniques, we aim to discover new targets for specific disease models.
1. Developing New Whole-body Clearing Techniques
2. New Targeted Formulations
3. Connections Between the Pharmacology and Physiological Systems in Disease
Publications
A deep-learning framework reveals whole-body perturbations at cell level. Nature, 2026.
Whole-mouse immunolabeling at cellular resolution for comprehensive 3D atlases. Nature Protocols, 2026.
CAR-neutrophils produced in vivo to treat glioma. Nature Biomedical Engineering, 2026.
Imaging of nanocarriers across entire mouse bodies at single-cell resolution. Nature Biotechnology, 2025.
Whole-body cellular mapping in mouse using standard IgG antibodies. Nature Biotechnology, 2023.
Immune-mediated denervation of the pineal gland underlies sleep disturbance in cardiac disease. Science, 2023.